Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCU4 / CELR2_HUMAN
Protein Name Cadherin EGF LAG seven-pass G-type receptor 2 precursor
Gene Name Name: CELSR2
Synonyms:CDHF10,EGFL2,KIAA0279,MEGF3;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCU4
DAG View
PRO Name cadherin EGF LAG seven-pass G-type receptor 2 (human)
Definition A cadherin EGF LAG seven-pass G-type receptor 2 that is encoded in the genome of human.
Short Label hCELSR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCU4 (CELSR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y681 Phosphorylation PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
Y1033 Phosphorylation PhosphoSitePlus
T1035 Phosphorylation PhosphoSitePlus
N1076 N-Glycosylation GlyGen 29741879
T1121 Phosphorylation PhosphoSitePlus
S1214 Phosphorylation PhosphoSitePlus
T1287 O-Glycosylation GlyGen 32574038
S1305 Phosphorylation PhosphoSitePlus
K1462 Ubiquitination PhosphoSitePlus
N1501 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N1565 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N1900 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N2043 N-Glycosylation GlyGen 23090970, 24190977
N2061 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S2072 O-Glycosylation GlyGen 32574038, 35138101, 35289036
K2121 Ubiquitination PhosphoSitePlus
T2212 O-Glycosylation GlyGen 30459171
S2608 Phosphorylation IEDB 32387766
K2637 Ubiquitination PhosphoSitePlus
S2642 Phosphorylation HPRD   phospho.ELM 18669648
S2648 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y2650 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
Y2656 Phosphorylation PhosphoSitePlus
Y2659 Phosphorylation PhosphoSitePlus
S2672 Phosphorylation PhosphoSitePlus
K2674 Ubiquitination PhosphoSitePlus
S2675 Phosphorylation PhosphoSitePlus
Y2679 Phosphorylation PhosphoSitePlus
S2776 Phosphorylation PhosphoSitePlus
T2777 Phosphorylation PhosphoSitePlus
K2787 Ubiquitination PhosphoSitePlus
S2823 Phosphorylation PhosphoSitePlus
S2868 Phosphorylation HPRD   phospho.ELM 18669648
S2869 Phosphorylation HPRD   phospho.ELM 18669648
S2871 Phosphorylation HPRD   phospho.ELM 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2642 L2642 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K2674 N2674 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]