iPTMnet Report for Q9HCD6 (TANC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCD6 / TANC2_HUMAN
Protein Name Protein TANC2
Gene Name Name: TANC2
Synonyms:KIAA1148,KIAA1636;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCD6
DAG View
PRO Name protein TANC2 (human)
Definition A protein TANC2 that is encoded in the genome of human.
Short Label hTANC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCD6 (TANC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus   UniProt 23186163
T171 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K212 Acetylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus   UniProt 23186163
S252 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
S252 Phosphorylation PhosphoSitePlus
S254 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
S254 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus   UniProt 23186163
S387 Phosphorylation PhosphoSitePlus
T391 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus   UniProt 23186163
S404 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
T434 Phosphorylation PhosphoSitePlus
T637 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
Y859 Phosphorylation PhosphoSitePlus
T1159 Phosphorylation PhosphoSitePlus
K1284 Ubiquitination PhosphoSitePlus
K1316 Acetylation PhosphoSitePlus
S1442 Phosphorylation PhosphoSitePlus   UniProt 15144186
S1445 Phosphorylation PhosphoSitePlus
S1446 Phosphorylation PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus
S1458 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1462 Phosphorylation PhosphoSitePlus
S1471 O-Glycosylation GlyGen 32574038
S1476 Phosphorylation PhosphoSitePlus
S1517 Phosphorylation PhosphoSitePlus
S1530 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1534 Phosphorylation PhosphoSitePlus
R1543 Methylation PhosphoSitePlus
S1545 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1556 Phosphorylation PhosphoSitePlus
S1558 Phosphorylation PhosphoSitePlus
S1560 Phosphorylation PhosphoSitePlus
S1579 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 27869121
S1582 Phosphorylation PhosphoSitePlus
K1583 Acetylation PhosphoSitePlus
K1609 Ubiquitination PhosphoSitePlus
S1619 Phosphorylation PhosphoSitePlus
S1646 O-Glycosylation GlyGen 32574038
S1647 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
S1647 Phosphorylation PhosphoSitePlus
S1663 Phosphorylation PhosphoSitePlus
R1700 Methylation PhosphoSitePlus
Y1705 Phosphorylation PhosphoSitePlus
R1706 Methylation PhosphoSitePlus
R1710 Methylation PhosphoSitePlus
T1714 Phosphorylation PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
S1722 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1725 Phosphorylation PhosphoSitePlus
Y1726 Phosphorylation PhosphoSitePlus
S1738 Phosphorylation PhosphoSitePlus
S1739 Phosphorylation PhosphoSitePlus
S1740 Phosphorylation PhosphoSitePlus
S1744 Phosphorylation PhosphoSitePlus
S1748 Phosphorylation PhosphoSitePlus
R1770 Methylation PhosphoSitePlus
S1775 Phosphorylation PhosphoSitePlus
R1781 Methylation PhosphoSitePlus
S1819 Phosphorylation PhosphoSitePlus
C1820 S-Nitrosylation dbSNO 26338901
S1824 Phosphorylation PhosphoSitePlus
S1827 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1829 Phosphorylation PhosphoSitePlus
S1840 Phosphorylation IEDB 32387766
Y1858 Phosphorylation PhosphoSitePlus
S1892 Phosphorylation PhosphoSitePlus
T1906 Phosphorylation PhosphoSitePlus
Y1919 Phosphorylation PhosphoSitePlus
Y1920 Phosphorylation PhosphoSitePlus
S1921 Phosphorylation PhosphoSitePlus
S1939 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
S1939 Phosphorylation PhosphoSitePlus
S1942 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
K1948 Ubiquitination PhosphoSitePlus
T1952 O-Glycosylation GlyGen 29351928, 30379171, 32574038, ...31492838, 30620550, 35132862, 31373491, 35289036, 35254053, 28657654, 29237092
Y1964 Phosphorylation PhosphoSitePlus
S1977 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 N5 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S254 L254 Biomuta DOID:1324 / lung cancer [ cosmic ]
S294 F294 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
S294 Y294 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S398 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T417 A417 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S421 L421 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T434 A434 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K641 E641 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1456 F1456 Biomuta [ cosmic ]
S1457 I1457 Biomuta [ cosmic ]
S1458 T1458 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S1517 R1517 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1530 N1530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1534 F1534 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1543 W1543 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R1543 Q1543 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R1700 Q1700 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R1706 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1725 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1725 C1725 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S1740 I1740 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1744 F1744 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1781 H1781 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R1781 C1781 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1819 P1819 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1824 L1824 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S1827 T1827 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1829 A1829 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T1906 A1906 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1919 N1919 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1920 D1920 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1942 F1942 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1977 F1977 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]