iPTMnet Report for Q9HCB6 (SPON1)
Protein Information
UniProt AC / UniProt ID | Q9HCB6 / SPON1_HUMAN |
Protein Name | Spondin-1 precursor |
Gene Name | Name: SPON1 Synonyms:KIAA0762,VSGP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HCB6 |
PRO Name | spondin-1 (human) |
Definition | A spondin-1 that is encoded in the genome of human. |
Short Label | hSPON1 |
Category | organism-gene |
Q9HCB6 (SPON1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
S11 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y43 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y58 | Phosphorylation | score1 | PhosphoSitePlus | |||
T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y170 | Phosphorylation | score1 | PhosphoSitePlus | |||
T192 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171 | ||
N214 | N-Glycosylation | score4 | GlyGen UniProt | 23090970, 29741879, 24190977, ... | ||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
W448 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W451 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W507 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W510 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W564 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W620 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W623 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
W674 | C-Glycosylation | score3 | GlyGen UniProt | 12096136 | ||
S725 | Phosphorylation | score1 | PhosphoSitePlus | |||
S747 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S40 | * | Biomuta | DOID:1324 / lung cancer [ cosmic, tcga ] | |
W448 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
W620 | L620 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S725 | F725 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S747 | T747 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |