iPTMnet Report for Q9HC29 (NOD2)
Protein Information
UniProt AC / UniProt ID | Q9HC29 / NOD2_HUMAN |
Protein Name | Nucleotide-binding oligomerization domain-containing protein 2 |
Gene Name | Name: NOD2 Synonyms:CARD15; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HC29 |
PRO Name | nucleotide-binding oligomerization domain-containing protein 2 (human) |
Definition | A nucleotide-binding oligomerization domain-containing protein 2 that is encoded in the genome of human. |
Short Label | hNOD2 |
Category | organism-gene |
Q9HC29 (NOD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
T239 | Phosphorylation | score1 | PhosphoSitePlus | |||
S402 | Phosphorylation | score1 | PhosphoSitePlus | |||
T424 | Phosphorylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S493 | Phosphorylation | score1 | PhosphoSitePlus | |||
K655 | Ubiquitination | score1 | PhosphoSitePlus | |||
C693 | Methylation | score1 | IEDB | 31844290 | ||
K717 | Acetylation | score1 | PhosphoSitePlus | |||
K731 | Acetylation | score1 | PhosphoSitePlus | |||
S745 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y747 | Phosphorylation | score1 | PhosphoSitePlus | |||
S983 | Phosphorylation | score1 | PhosphoSitePlus | |||
S984 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1022 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1024 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T189 | M189 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S402 | F402 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S477 | L477 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S493 | Y493 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
C693 | F693 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
C693 | Y693 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K731 | R731 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y747 | F747 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |