iPTMnet Report for Q9HC10 (OTOF)
Protein Information
UniProt AC / UniProt ID | Q9HC10 / OTOF_HUMAN |
Protein Name | Otoferlin |
Gene Name | Name: OTOF Synonyms:FER1L2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HC10 |
PRO Name | otoferlin (human) |
Definition | An otoferlin that is encoded in the genome of human. |
Short Label | hOTOF |
Category | organism-gene |
Q9HC10 (OTOF) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
K239 | Acetylation | score1 | PhosphoSitePlus | |||
T286 | Phosphorylation | score1 | PhosphoSitePlus | |||
S320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y755 | Phosphorylation | score1 | PhosphoSitePlus | |||
K834 | Ubiquitination | score1 | PhosphoSitePlus | |||
K896 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1215 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1216 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1231 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1332 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1335 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1338 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1340 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1349 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1368 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1532 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1534 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1741 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1753 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1757 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1758 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T1193 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T20 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T149 | M149 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
S159 | N159 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S177 | F177 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S320 | L320 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
S320 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S1335 | Y1335 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T1741 | K1741 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1758 | T1758 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |