iPTMnet Report for Q9HBE5 (IL21R)
Protein Information
UniProt AC / UniProt ID | Q9HBE5 / IL21R_HUMAN |
Protein Name | Interleukin-21 receptor precursor |
Gene Name | Name: IL21R Synonyms:NILR;ORFNames:UNQ3121/PRO10273; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HBE5 |
PRO Name | interleukin-21 receptor (human) |
Definition | An interleukin-21 receptor that is encoded in the genome of human. |
Short Label | hIL21R |
Category | organism-gene |
Q9HBE5 (IL21R) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C65 | Methylation | score1 | IEDB | 31844290 | ||
N73 | N-Glycosylation | score3 | GlyGen UniProt | 22235133 | ||
N125 | N-Glycosylation | score1 | IEDB | 26280087 | ||
S170 | Phosphorylation | score1 | IEDB | 35494241 | ||
R201 | Methylation | score1 | PhosphoSitePlus | |||
W214 | C-Glycosylation | score3 | GlyGen UniProt | 22235133 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R201 | W201 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] | |
W214 | C214 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
W214 | R214 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |