iPTMnet Report for Q9H9Y6 (POLR1B)
Protein Information
UniProt AC / UniProt ID | Q9H9Y6 / RPA2_HUMAN |
Protein Name | DNA-directed RNA polymerase I subunit RPA2 |
Gene Name | Name: POLR1B |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H9Y6 |
PRO Name | DNA-directed RNA polymerase I subunit RPA2 (human) |
Definition | A DNA-directed RNA polymerase I subunit RPA2 that is encoded in the genome of human. |
Short Label | hPOLR1B |
Category | organism-gene |
Q9H9Y6 (POLR1B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K17 | Methylation | score1 | PhosphoSitePlus | |||
K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
C103 | Methylation | score1 | IEDB | 31844290 | ||
Y136 | Phosphorylation | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
C307 | Methylation | score1 | IEDB | 31844290 | ||
C331 | Methylation | score1 | IEDB | 31844290 | ||
C361 | Methylation | score1 | IEDB | 31844290 | ||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
C471 | Methylation | score1 | IEDB | 31844290 | ||
C518 | Methylation | score1 | IEDB | 31844290 | ||
K582 | Ubiquitination | score1 | PhosphoSitePlus | |||
C617 | Methylation | score1 | IEDB | 31844290 | ||
K693 | Methylation | score1 | PhosphoSitePlus | |||
K693 | Ubiquitination | score1 | PhosphoSitePlus | |||
K784 | Ubiquitination | score1 | PhosphoSitePlus | |||
K786 | Ubiquitination | score1 | PhosphoSitePlus | |||
K797 | Ubiquitination | score1 | PhosphoSitePlus | |||
K806 | Ubiquitination | score1 | PhosphoSitePlus | |||
K844 | Ubiquitination | score1 | PhosphoSitePlus | |||
K853 | Ubiquitination | score1 | PhosphoSitePlus | |||
K863 | Methylation | score1 | PhosphoSitePlus | |||
K863 | Ubiquitination | score1 | PhosphoSitePlus | |||
K882 | Ubiquitination | score1 | PhosphoSitePlus | |||
C944 | Methylation | score1 | IEDB | 31844290 | ||
Y971 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y998 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y999 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1009 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1051 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K1083 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1095 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1118 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K144 | N144 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K144 | M144 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K272 | N272 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
C331 | Y331 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K853 | E853 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y999 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1051 | F1051 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |