iPTMnet Report for Q9H9S3 (SEC61A2)
Protein Information
UniProt AC / UniProt ID | Q9H9S3 / S61A2_HUMAN |
Protein Name | Protein transport protein Sec61 subunit alpha isoform 2 |
Gene Name | Name: SEC61A2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H9S3 |
PRO Name | protein transport protein Sec61 subunit alpha isoform 2 (human) |
Definition | A protein transport protein Sec61 subunit alpha isoform 2 that is encoded in the genome of human. |
Short Label | hSEC61A2 |
Category | organism-gene |
Q9H9S3 (SEC61A2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
T75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
T86 | Phosphorylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
T105 | Phosphorylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
R405 | Methylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S33 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T105 | S105 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K388 | R388 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K392 | E392 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
K395 | T395 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |