iPTMnet Report for Q9H9D4 (ZNF408)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H9D4 / ZN408_HUMAN
Protein Name Zinc finger protein 408
Gene Name Name: ZNF408
Synonyms:PFM14,PRDM17;
Organism Homo sapiens (Human)

PRO ID PR:Q9H9D4
DAG View
PRO Name zinc finger protein 408 (human)
Definition A zinc finger protein 408 that is encoded in the genome of human.
Short Label hZNF408
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H9D4 (ZNF408) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S150 Phosphorylation IEDB 35494241
S225 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S338 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
T491 Phosphorylation PhosphoSitePlus
K494 Sumoylation PhosphoSitePlus
R512 Methylation PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
K593 Sumoylation PhosphoSitePlus
K605 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S150 T150 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S225 C225 Biomuta DOID:1612 / breast cancer [ cosmic ]
R512 H512 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R512 C512 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S574 F574 Biomuta DOID:4159 / skin cancer [ cosmic ]