iPTMnet Report for Q9H981 (ACTR8)
Protein Information
UniProt AC / UniProt ID | Q9H981 / ARP8_HUMAN |
Protein Name | Actin-related protein 8 |
Gene Name | Name: ACTR8 Synonyms:ARP8,INO80N; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H981 |
PRO Name | actin-related protein 8 (human) |
Definition | An actin-related protein 8 that is encoded in the genome of human. |
Short Label | hACTR8 |
Category | organism-gene |
Q9H981 (ACTR8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S132 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983 | ||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y180 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K225 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y329 | Phosphorylation | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18669648, 23186163, 29759113, ... | ||
Y424 | Phosphorylation | score1 | PhosphoSitePlus | |||
K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
S446 | Phosphorylation | score1 | PhosphoSitePlus | |||
K447 | Acetylation | score1 | PhosphoSitePlus | |||
K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
K507 | Methylation | score1 | PhosphoSitePlus | |||
K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
K513 | Ubiquitination | score1 | PhosphoSitePlus | |||
S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
K577 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S132 | Phosphorylation | score0 | HPRD | 17924679, 19691289, 20068231, ... | ||
Y309 | Phosphorylation | score0 | HPRD | 20068231 | ||
S315 | Phosphorylation | score0 | HPRD | 20068231 | ||
S412 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S444 | Phosphorylation | score0 | HPRD | 20068231 | ||
S562 | Phosphorylation | score0 | HPRD | 20068231 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | Q9H981 (ACTR8) | S412 | Q9ULG1 (INO80) | unknown | eFIP | 29759113 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y180 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
Y219 | C219 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |