iPTMnet Report for Q9H8S9 (MOB1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H8S9 / MOB1A_HUMAN
Protein Name MOB kinase activator 1A
Gene Name Name: MOB1A
Synonyms:C2orf6,MOB4B,MOBK1B,MOBKL1B;
Organism Homo sapiens (Human)

PRO ID PR:Q9H8S9
DAG View
PRO Name MOB kinase activator 1A (human)
Definition A MOB kinase activator 1A that is encoded in the genome of human.
Short Label hMOB1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H8S9 (MOB1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378, 12665801
S2 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
K11 Acetylation PhosphoSitePlus
T12 Phosphorylation Q13043 (STK4) , Q13188 (STK3) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18328708, 23431053, 21808241, ...19919647, 26108669
K16 Acetylation PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
S23 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
Y26 Phosphorylation PhosphoSitePlus   RLIMS-P 28675297
K30 Ubiquitination PhosphoSitePlus
T35 Phosphorylation Q13043 (STK4) , Q13188 (STK3) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18328708, 23431053, 27555231, ...32973917, 21808241, 19919647, 26108669
S38 Phosphorylation PhosphoSitePlus
T74 Phosphorylation Q13188 (STK3) PhosphoSitePlus   RLIMS-P   Signor   UniProt 18362890
Y95 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
T181 Phosphorylation UniProt 18362890
S213 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
S23 Phosphorylation HPRD 17287340
T35 Phosphorylation HPRD 18691976, 18669648, 18212344, ...20068231
S38 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048409 (hMOB1A/InitMet-/Phos:1) pT12,pT35 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9H8S9 (MOB1A) T12 Q15208 (STK38) unknown eFIP 27213455


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K16 N16 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K17 R17 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y95 F95 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K104 E104 Biomuta DOID:9256 / colorectal cancer [ cosmic ]