iPTMnet Report for Q9H8G2 (CAAP1)
Protein Information
UniProt AC / UniProt ID | Q9H8G2 / CAAP1_HUMAN |
Protein Name | Caspase activity and apoptosis inhibitor 1 |
Gene Name | Name: CAAP1 Synonyms:C9orf82,CAAP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H8G2 |
PRO Name | caspase activity and apoptosis inhibitor 1 (human) |
Definition | A caspase activity and apoptosis inhibitor 1 that is encoded in the genome of human. |
Short Label | hCAAP1 |
Category | organism-gene |
Q9H8G2 (CAAP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S89 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
T90 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S92 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S93 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S94 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
S120 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S187 | Phosphorylation | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
S203 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
S203 | Phosphorylation | O14757 (CHEK1) | score1 | PhosphoSitePlus | 21851590 | |
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
S221 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
C226 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S232 | Phosphorylation | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
S311 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S312 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 15302935, ... | ||
K349 | Acetylation | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
K353 | Acetylation | score1 | PhosphoSitePlus | |||
K359 | Acetylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S6 | Phosphorylation | score0 | HPRD | 20068231 | ||
S7 | Phosphorylation | score0 | HPRD | 20068231 | ||
S89 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18767875, ... | ||
T90 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 19664995, ... | ||
S92 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 19664995 | ||
S93 | Phosphorylation | score0 | HPRD | 18669648 | ||
S94 | Phosphorylation | score0 | HPRD | 19413330, 18669648 | ||
S203 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18767875, ... | ||
S221 | Phosphorylation | score0 | HPRD | 17525332 | ||
S311 | Phosphorylation | score0 | HPRD | 18669648, 19664995, 20068231 | ||
S312 | Phosphorylation | score0 | HPRD | 19413330, 15302935, 19664994, ... |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S94 | T94 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S96 | L96 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S120 | I120 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K189 | N189 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S213 | F213 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ] | |
C226 | Y226 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S311 | P311 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
S312 | R312 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S312 | C312 | Biomuta | DOID:1612 / breast cancer [ icgc ] |