iPTMnet Report for Q9H7M9 (VSIR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7M9 / VISTA_HUMAN
Protein Name V-type immunoglobulin domain-containing suppressor of T-cell activation precursor
Gene Name Name: VSIR
Synonyms:C10orf54,SISP1;ORFNames:PP2135,UNQ730/PRO1412;
Organism Homo sapiens (Human)

PRO ID PR:Q9H7M9
DAG View
PRO Name V-type immunoglobulin domain-containing suppressor of T-cell activation (human)
Definition A V-type immunoglobulin domain-containing suppressor of T-cell activation that is encoded in the genome of human.
Short Label hVSIR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7M9 (VSIR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation HPRD 20068231
T37 O-Glycosylation GlyGen 29351928
N49 N-Glycosylation GlyGen 24190977
K62 Ubiquitination PhosphoSitePlus
N128 N-Glycosylation GlyGen 23090970, 24190977
S235 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20058876, 23186163, 19690332, ...24275569
S248 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
K258 Ubiquitination PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S280 Phosphorylation HPRD   PhosphoSitePlus 20068231
S283 Phosphorylation PhosphoSitePlus
T284 Phosphorylation HPRD   PhosphoSitePlus 20068231
S287 Phosphorylation HPRD   PhosphoSitePlus 20068231
S298 Phosphorylation PhosphoSitePlus
S305 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T5 K5 Biomuta DOID:3571 / liver cancer [ cosmic ]
T37 M37 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
Y265 C265 Biomuta DOID:184 / bone cancer [ cosmic ]
Y265 F265 Biomuta DOID:3571 / liver cancer [ cosmic ]
S272 F272 Biomuta DOID:4159 / skin cancer [ cosmic ]
S280 L280 Biomuta DOID:1324 / lung cancer [ cosmic ]
T284 S284 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S305 Y305 Biomuta DOID:4159 / skin cancer [ cosmic ]