iPTMnet Report for Q9H7L9 (SUDS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H7L9 / SDS3_HUMAN
Protein Name Sin3 histone deacetylase corepressor complex component SDS3
Gene Name Name: SUDS3
Synonyms:SAP45,SDS3;
Organism Homo sapiens (Human)

PRO ID PR:Q9H7L9
DAG View
PRO Name Sin3 histone deacetylase corepressor complex component SDS3 (human)
Definition A Sin3 histone deacetylase corepressor complex component SDS3 that is encoded in the genome of human.
Short Label hSUDS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H7L9 (SUDS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S2 Acetylation UniProt 21406692
S2 Phosphorylation HPRD 20068231
S32 Phosphorylation PhosphoSitePlus   UniProt 21406692
S39 Phosphorylation HPRD   PhosphoSitePlus 20068231
S45 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 15302935, ...18318008, 19651622, 18669648, 24275569, 20166139, 20068231
T49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18318008, 19651622, ...18669648, 24275569, 20166139, 20068231
S53 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231
T55 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983
Y65 Phosphorylation PhosphoSitePlus
K69 Sumoylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y209 Phosphorylation HPRD   PhosphoSitePlus 20230923
S228 Phosphorylation neXtProt   PhosphoSitePlus   UniProt 15489224, 21406692
S234 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20230923, ...18847512, 19690332, 19651622, 18669648, 24275569, 20166139, 19415658, 20068231
S236 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus 17287340, 17081983, 20230923, ...18847512, 19651622, 18669648, 20166139, 19415658, 20068231
S237 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20230923, ...18847512, 19651622, 18669648, 20166139, 19415658, 20068231
T244 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20166139, 18669648, 17287340, ...18847512
S248 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K261 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049382 (hSUDS3/InitMet-/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K69 E69 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K69 N69 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y73 C73 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
Y73 D73 Biomuta DOID:3565 / meningioma [ cosmic ]
T167 S167 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S174 A174 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S237 C237 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S248 F248 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S305 N305 Biomuta DOID:363 / uterine cancer [ icgc ]