iPTMnet Report for Q9H6Z4 (RANBP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6Z4 / RANB3_HUMAN
Protein Name Ran-binding protein 3
Gene Name Name: RANBP3
Organism Homo sapiens (Human)

PRO ID PR:Q9H6Z4
DAG View
PRO Name Ran-binding protein 3 (human)
Definition A Ran-binding protein 3 that is encoded in the genome of human.
Short Label hRANBP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6Z4 (RANBP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
K21 Acetylation PhosphoSitePlus   UniProt 19608861
S27 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus   UniProt 24275569
S96 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S100 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S101 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...24275569
Y115 Phosphorylation PhosphoSitePlus
C116 Methylation IEDB 31844290
C116 S-Nitrosylation dbSNO 26338901
T124 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S125 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S126 Phosphorylation P51812 (RPS6KA3) , P31749 (AKT1) , Q15418 (RPS6KA1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17525332, 23186163, 18669648, ...18280241
T128 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S133 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
K145 Ubiquitination PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
C203 S-Nitrosylation dbSNO 26338901
S211 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T214 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T292 Phosphorylation IEDB   PhosphoSitePlus 32357974
Y298 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S333 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332
S353 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S355 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S357 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S358 Phosphorylation PhosphoSitePlus
S359 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648
T363 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus   UniProt 23186163
K378 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
Y501 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S539 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 20068231
S96 Phosphorylation HPRD 20166139, 18669648, 17081983
S100 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
S101 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
S108 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
Y115 Phosphorylation HPRD 17081983
T124 Phosphorylation HPRD 18077418, 18669648
S125 Phosphorylation HPRD 19413330, 18077418, 18669648, ...19664995
S126 Phosphorylation HPRD 19413330, 17525332, 18669648
T128 Phosphorylation HPRD 18669648
S133 Phosphorylation HPRD 17525332, 18077418
S186 Phosphorylation HPRD 18077418
S211 Phosphorylation HPRD 19413330, 18077418, 18669648
T214 Phosphorylation HPRD 19413330
S219 Phosphorylation HPRD 19664994
S333 Phosphorylation HPRD 20166139, 18669648, 20068231, ...20230923
S353 Phosphorylation HPRD 18669648
S355 Phosphorylation HPRD 18669648
S357 Phosphorylation HPRD 18669648
S359 Phosphorylation HPRD 17525332, 18669648
S533 Phosphorylation HPRD 19413330, 19664995
S539 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 20068231
S96 Phosphorylation HPRD 20166139, 18669648, 17081983
S100 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
S101 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
S108 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
Y115 Phosphorylation HPRD 17081983
T124 Phosphorylation HPRD 18077418, 18669648
S125 Phosphorylation HPRD 19413330, 18077418, 18669648, ...19664995
S126 Phosphorylation HPRD 19413330, 17525332, 18669648
T128 Phosphorylation HPRD 18669648
S133 Phosphorylation HPRD 17525332, 18077418
S186 Phosphorylation HPRD 18077418
S211 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18077418, 18669648
T214 Phosphorylation HPRD 19413330
S219 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S328 Phosphorylation HPRD 20166139, 18669648, 20068231, ...20230923
S348 Phosphorylation HPRD 18669648
S350 Phosphorylation HPRD 18669648
S352 Phosphorylation HPRD 18669648
S354 Phosphorylation HPRD 18669648
S528 Phosphorylation HPRD 19413330, 19664995
S534 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation HPRD 20166139, 18669648, 17081983
S32 Phosphorylation HPRD 19413330, 20166139, 18669648, ...17081983, 19415658
S33 Phosphorylation HPRD   PhosphoSitePlus 19413330, 17081983, 18669648, ...20166139, 19415658
S40 Phosphorylation HPRD   PhosphoSitePlus 19413330, 17081983, 18669648, ...20166139, 19415658
Y47 Phosphorylation HPRD 17081983
T56 Phosphorylation HPRD 18077418, 18669648
S57 Phosphorylation HPRD 19413330, 18077418, 18669648, ...19664995
S58 Phosphorylation HPRD   PhosphoSitePlus 19413330, 17525332, 18669648
T60 Phosphorylation HPRD 18669648
S65 Phosphorylation HPRD 17525332, 18077418
S118 Phosphorylation HPRD 18077418
S143 Phosphorylation HPRD 19413330, 18077418, 18669648
T146 Phosphorylation HPRD 19413330
S151 Phosphorylation HPRD 19664994
S265 Phosphorylation HPRD 20166139, 18669648, 20068231, ...20230923
S285 Phosphorylation HPRD 18669648
S287 Phosphorylation HPRD 18669648
S289 Phosphorylation HPRD 18669648
S291 Phosphorylation HPRD 18669648
S465 Phosphorylation HPRD 19413330, 19664995
S471 Phosphorylation HPRD 19413330, 18669648, 20068231, ...18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 C40 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y47 H47 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S72 L72 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:1319 / brain cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S108 C108 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y115 H115 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S143 F143 Biomuta DOID:1319 / brain cancer [ icgc ]
S211 F211 Biomuta DOID:1319 / brain cancer [ icgc ]
T292 M292 Biomuta DOID:3571 / liver cancer [ cosmic ]
S358 L358 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
T457 S457 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S465 F465 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S528 F528 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S533 F533 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]