iPTMnet Report for Q9H6R7 (WDCP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H6R7 / WDCP_HUMAN
Protein Name WD repeat and coiled-coil-containing protein
Gene Name Name: WDCP
Synonyms:C2orf44;ORFNames:PP384;
Organism Homo sapiens (Human)

PRO ID PR:Q9H6R7
DAG View
PRO Name WD repeat and coiled-coil-containing protein (human)
Definition A WD repeat and coiled-coil-containing protein that is encoded in the genome of human.
Short Label hWDCP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H6R7 (WDCP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T11 O-Glycosylation GlyGen 34105348
K47 Ubiquitination PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
Y249 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163
K326 Acetylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
T331 Phosphorylation PhosphoSitePlus
K333 Acetylation PhosphoSitePlus
C361 Methylation IEDB 31844290
S417 Phosphorylation PhosphoSitePlus
Y422 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus   UniProt 23186163
S486 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus   UniProt 18691976
S510 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus   UniProt 18691976
S529 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T530 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S535 Phosphorylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
S686 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S688 Phosphorylation PhosphoSitePlus
S690 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S695 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S299 Phosphorylation HPRD 18691976
S466 Phosphorylation HPRD 18691976
S468 Phosphorylation HPRD 18691976
S501 Phosphorylation HPRD 18691976
S510 Phosphorylation HPRD 18691976
S523 Phosphorylation HPRD 18691976
S686 Phosphorylation HPRD 18669648
S688 Phosphorylation HPRD 18691976
S690 Phosphorylation HPRD 19651622, 18691976, 18669648, ...18767875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K47 R47 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S299 Y299 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T331 K331 Biomuta DOID:3571 / liver cancer [ cosmic ]
T331 M331 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K333 E333 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
C361 S361 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S417 L417 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
S466 R466 Biomuta DOID:1324 / lung cancer [ cosmic ]
S523 L523 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K552 R552 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S686 C686 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S696 Y696 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]