iPTMnet Report for Q9H5U6 (ZCCHC4)
Protein Information
| UniProt AC / UniProt ID | Q9H5U6 / ZCHC4_HUMAN |
| Protein Name | rRNA N6-adenosine-methyltransferase ZCCHC4 |
| Gene Name | Name: ZCCHC4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H5U6 |
| PRO Name | rRNA N6-adenosine-methyltransferase ZCCHC4 (human) |
| Definition | An rRNA N6-adenosine-methyltransferase ZCCHC4 that is encoded in the genome of human. |
| Short Label | hZCCHC4 |
| Category | organism-gene |
Q9H5U6 (ZCCHC4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K123 | Acetylation | score1 | PhosphoSitePlus | |||
| K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R194 | Methylation | score1 | PhosphoSitePlus | |||
| C240 | Methylation | score1 | IEDB | 31844290 | ||
| T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T362 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K469 | Acetylation | score1 | PhosphoSitePlus | |||
| K475 | Acetylation | score1 | PhosphoSitePlus | |||
| S479 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
| T487 | Phosphorylation | score1 | phospho.ELM | 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K82 | N82 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
| C240 | F240 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T362 | I362 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T362 | S362 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K475 | N475 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
DAG View