iPTMnet Report for Q9H5U6 (ZCCHC4)
Protein Information
UniProt AC / UniProt ID | Q9H5U6 / ZCHC4_HUMAN |
Protein Name | rRNA N6-adenosine-methyltransferase ZCCHC4 |
Gene Name | Name: ZCCHC4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H5U6 |
PRO Name | rRNA N6-adenosine-methyltransferase ZCCHC4 (human) |
Definition | An rRNA N6-adenosine-methyltransferase ZCCHC4 that is encoded in the genome of human. |
Short Label | hZCCHC4 |
Category | organism-gene |
Q9H5U6 (ZCCHC4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
K123 | Acetylation | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
R194 | Methylation | score1 | PhosphoSitePlus | |||
C240 | Methylation | score1 | IEDB | 31844290 | ||
T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
T362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
K469 | Acetylation | score1 | PhosphoSitePlus | |||
K475 | Acetylation | score1 | PhosphoSitePlus | |||
S479 | Phosphorylation | score1 | phospho.ELM | 17081983 | ||
T487 | Phosphorylation | score1 | phospho.ELM | 17081983 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K82 | N82 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] | |
C240 | F240 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T362 | I362 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T362 | S362 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K475 | N475 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |