iPTMnet Report for Q9H4F1 (ST6GALNAC4)
Protein Information
UniProt AC / UniProt ID | Q9H4F1 / SIA7D_HUMAN |
Protein Name | Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase |
Gene Name | Name: ST6GALNAC4 Synonyms:SIAT3C,SIAT7D; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H4F1 |
PRO Name | alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (human) |
Definition | An alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase that is encoded in the genome of human. |
Short Label | hST6GALNAC4 |
Category | organism-gene |
Q9H4F1 (ST6GALNAC4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S137 | O-Glycosylation | score1 | GlyGen | 35289036 | ||
T173 | Phosphorylation | score1 | PhosphoSitePlus | |||
T217 | Phosphorylation | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
S298 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T173 | A173 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |