Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H488 / OFUT1_HUMAN
Protein Name GDP-fucose protein O-fucosyltransferase 1 precursor
Gene Name Name: POFUT1
Synonyms:FUT12,KIAA0180;
Organism Homo sapiens (Human)

PRO ID PR:Q9H488
DAG View
PRO Name GDP-fucose protein O-fucosyltransferase 1 (human)
Definition A GDP-fucose protein O-fucosyltransferase 1 that is encoded in the genome of human.
Short Label hPOFUT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H488 (POFUT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N62 N-Glycosylation GlyGen   UniProt 28334865
Y87 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
N160 N-Glycosylation GlyGen   UniProt 29741879, 19159218
Y211 Phosphorylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N62 S62 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]