iPTMnet Report for Q9H410 (DSN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H410 / DSN1_HUMAN
Protein Name Kinetochore-associated protein DSN1 homolog
Gene Name Name: DSN1
Synonyms:C20orf172,MIS13;
Organism Homo sapiens (Human)

PRO ID PR:Q9H410
DAG View
PRO Name kinetochore-associated protein DSN1 homolog (human)
Definition A kinetochore-associated protein DSN1 that is encoded in the genome of human.
Short Label hDSN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H410 (DSN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 O-Glycosylation GlyGen 30379171
K13 Sumoylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
S27 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S28 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 16565220
S30 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220, 22067460, ...18669648, 19690332, 20068231
S41 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S49 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S57 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S58 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 17081983, ...20068231
K61 Sumoylation PhosphoSitePlus
S68 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S75 Phosphorylation PhosphoSitePlus
K76 Sumoylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S77 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 18669648, 23186163
S81 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 22067460, ...18669648, 20068231
S86 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983, 18220336
S88 Phosphorylation PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
S100 Phosphorylation Q96GD4 (AURKB) PhosphoSitePlus   RLIMS-P   Signor 18640974, 22801782, 20471944
K108 Sumoylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
S109 Phosphorylation Q96GD4 (AURKB) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20471944, 23186163, 18640974, ...32027339, 22067460
T118 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S125 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163
S131 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
K132 Ubiquitination PhosphoSitePlus
K157 Sumoylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T245 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K253 Sumoylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
C287 Methylation IEDB 31844290
C312 Methylation IEDB 31844290
K322 Ubiquitination PhosphoSitePlus
S331 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 23186163
K338 Sumoylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
S350 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation HPRD 20068231
S3 Phosphorylation HPRD 20068231
T5 Phosphorylation HPRD 20068231
S7 Phosphorylation HPRD 19007248, 20068231
T20 Phosphorylation HPRD 18691976
S27 Phosphorylation HPRD 18691976, 20068231
S28 Phosphorylation HPRD 19651622, 18669648, 20068231, ...16565220
S30 Phosphorylation HPRD 19651622, 18691976, 18669648, ...20068231, 16565220
T38 Phosphorylation HPRD 19007248, 20068231
S41 Phosphorylation HPRD 19007248, 19691289
S49 Phosphorylation HPRD 19007248
S57 Phosphorylation HPRD 18691976, 18669648, 20068231
S58 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
S68 Phosphorylation HPRD 19007248
S77 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
S81 Phosphorylation HPRD 19691289, 18452278, 19651622, ...18669648, 19007248, 20068231
S88 Phosphorylation HPRD 19651622
S109 Phosphorylation HPRD 20068231
S123 Phosphorylation HPRD 19007248, 19691289
S125 Phosphorylation HPRD 19007248, 19691289
S244 Phosphorylation HPRD 17081983, 19007248
S331 Phosphorylation HPRD 19007248, 20068231, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T20 I20 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S28 I28 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S57 C57 Biomuta DOID:4159 / skin cancer [ cosmic ]
S58 G58 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S75 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S77 P77 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S77 C77 Biomuta DOID:3571 / liver cancer [ cosmic ]
S86 F86 Biomuta DOID:4159 / skin cancer [ cosmic ]
S100 G100 Biomuta DOID:263 / kidney cancer [ cosmic ]
S109 L109 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
S125 G125 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K190 I190 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
C287 F287 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K338 N338 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S350 F350 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]