iPTMnet Report for Q9H3R5 (CENPH)
Protein Information
UniProt AC / UniProt ID | Q9H3R5 / CENPH_HUMAN |
Protein Name | Centromere protein H |
Gene Name | Name: CENPH Synonyms:ICEN35; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H3R5 |
PRO Name | centromere protein H (human) |
Definition | A centromere protein H that is encoded in the genome of human. |
Short Label | hCENPH |
Category | organism-gene |
Q9H3R5 (CENPH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S16 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19691289 | ||
R21 | Methylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
T68 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K76 | Ubiquitination | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K179 | Ubiquitination | score1 | PhosphoSitePlus | |||
K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R21 | L21 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S124 | I124 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K138 | N138 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
K171 | Q171 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K183 | R183 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |