iPTMnet Report for Q9H3P2 (NELFA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3P2 / NELFA_HUMAN
Protein Name Negative elongation factor A
Gene Name Name: NELFA
Synonyms:WHSC2;ORFNames:P/OKcl.15;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3P2
DAG View
PRO Name negative elongation factor A (human)
Definition A negative elongation factor A that is encoded in the genome of human.
Short Label hNELFA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3P2 (NELFA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
C44 Methylation IEDB 31844290
T60 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
C131 S-Nitrosylation dbSNO 26338901
C141 S-Nitrosylation dbSNO 26338901
T157 Phosphorylation P24941 (CDK2) PhosphoSitePlus   UniProt 23186163, 16964243, 18847512, ...19690332, 20068231
K161 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K190 Methylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
K200 Methylation PhosphoSitePlus
R202 Methylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus   UniProt 23186163
T227 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus   UniProt 23186163
T235 Phosphorylation PhosphoSitePlus
R238 Methylation PhosphoSitePlus
T239 Phosphorylation PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
K255 Acetylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K285 Acetylation PhosphoSitePlus
K288 Sumoylation PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
T328 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
T365 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K446 Methylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
Y521 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S244 Phosphorylation HPRD 15302935, 20068231
T246 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R202 L202 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R202 W202 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R202 Q202 Biomuta DOID:4159 / skin cancer [ cosmic ]