iPTMnet Report for Q9H3G5 (CPVL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H3G5 / CPVL_HUMAN
Protein Name Probable serine carboxypeptidase CPVL precursor
Gene Name Name: CPVL
Synonyms:VLP;ORFNames:PSEC0124,UNQ197/PRO223;
Organism Homo sapiens (Human)

PRO ID PR:Q9H3G5
DAG View
PRO Name probable serine carboxypeptidase CPVL (human)
Definition A probable serine carboxypeptidase CPVL that is encoded in the genome of human.
Short Label hCPVL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H3G5 (CPVL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y48 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus
T79 Phosphorylation PhosphoSitePlus
N81 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N132 N-Glycosylation GlyGen   UniProt 19159218
K269 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
N307 N-Glycosylation GlyGen 23090970, 29741879, 24190977
K331 Ubiquitination PhosphoSitePlus
N346 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
T348 O-Glycosylation GlyGen 23301498, 34019948, 22661428, ...30059200
Y383 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
Y411 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K53 E53 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K53 N53 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y74 N74 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T79 N79 Biomuta DOID:4159 / skin cancer [ cosmic ]
T79 I79 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N81 K81 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N81 S81 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T348 S348 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]