iPTMnet Report for Q9H330 (TMEM245)
Protein Information
| UniProt AC / UniProt ID | Q9H330 / TM245_HUMAN |
| Protein Name | Transmembrane protein 245 |
| Gene Name | Name: TMEM245 Synonyms:C9orf5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H330 |
| PRO Name | transmembrane protein 245 (human) |
| Definition | A transmembrane protein 245 that is encoded in the genome of human. |
| Short Label | hTMEM245 |
| Category | organism-gene |
DAG ViewQ9H330 (TMEM245) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T36 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 18669648, 23186163 | ||
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S324 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S327 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T329 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S330 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S332 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 15302935 | ||
| T334 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y531 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y533 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K541 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K544 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K549 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N551 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
| N552 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T553 | O-Glycosylation | score1 | GlyGen | 30059200, 35254053 | ||
| T553 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N575 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| S690 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S695 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K875 | Methylation | score1 | PhosphoSitePlus | |||
| K875 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S877 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S15 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
| S16 | Phosphorylation | score0 | HPRD | 17081983 | ||
| T36 | Phosphorylation | score0 | HPRD | 18691976, 18669648 | ||
| S330 | Phosphorylation | score0 | HPRD | 18578522, 18669648 | ||
| S332 | Phosphorylation | score0 | HPRD | 20166139, 18691976, 18578522, ... | ||
| T334 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S877 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K544 | * | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K544 | N544 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K544 | T544 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| N551 | K551 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S690 | F690 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
