iPTMnet Report for Q9H299 (SH3BGRL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H299 / SH3L3_HUMAN
Protein Name SH3 domain-binding glutamic acid-rich-like protein 3
Gene Name Name: SH3BGRL3
ORFNames:P1725;
Organism Homo sapiens (Human)

PRO ID PR:Q9H299
DAG View
PRO Name SH3 domain-binding glutamic acid-rich-like protein 3 (human)
Definition An SH3 domain-binding glutamic acid-rich-like protein 3 that is encoded in the genome of human.
Short Label hSH3BGRL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H299 (SH3BGRL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
R5 Methylation PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
R47 Methylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R47 S47 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R47 M47 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y74 H74 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y74 F74 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]