iPTMnet Report for Q9H204 (MED28)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H204 / MED28_HUMAN
Protein Name Mediator of RNA polymerase II transcription subunit 28
Gene Name Name: MED28
Synonyms:EG1;ORFNames:FKSG20;
Organism Homo sapiens (Human)

PRO ID PR:Q9H204
DAG View
PRO Name mediator of RNA polymerase II transcription subunit 28 (human)
Definition A mediator of RNA polymerase II transcription subunit 28 that is encoded in the genome of human.
Short Label hMED28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H204 (MED28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y64 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor 16899217
Y64 Phosphorylation P06239 (LCK) HPRD   neXtProt   PhosphoSitePlus   Signor 16899217
Y64 Phosphorylation P06241 (FYN) Signor 16899217
K83 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K176 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y64 Phosphorylation PRO 16899217


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000025633 (hMED28/iso:1/Phos:1) pY64 PRO 16899217


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000025633 (hMED28/iso:1/Phos:1) Interaction PR:P62993 (hGRB2) PRO 16899217
PR:P35240-1 (hNF2/iso:1) Interaction PR:Q9H204 (hMED28) PRO 15467741
PR:P35240-3 (hNF2/iso:2) Interaction PR:Q9H204 (hMED28) PRO 15467741


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K83 E83 Biomuta DOID:3571 / liver cancer [ cosmic ]
K98 T98 Biomuta DOID:363 / uterine cancer [ icgc ]