iPTMnet Report for Q9H0Z9 (RBM38)
Protein Information
| UniProt AC / UniProt ID | Q9H0Z9 / RBM38_HUMAN |
| Protein Name | RNA-binding protein 38 |
| Gene Name | Name: RBM38 Synonyms:RNPC1,SEB4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H0Z9 |
| PRO Name | RNA-binding protein 38 (human) |
| Definition | An RNA-binding protein 38 that is encoded in the genome of human. |
| Short Label | hRBM38 |
| Category | organism-gene |
DAG ViewQ9H0Z9 (RBM38) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R85 | Methylation | score1 | PhosphoSitePlus | |||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S195 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P Signor | 25823026, 24142875 | ||
| S195 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus Signor | 24142875 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q9H0Z9 (RBM38) | S195 | P06730 (EIF4E) | inhibited_association | eFIP | 35568694 | |
| Phosphorylation | Q9H0Z9 (RBM38) | S195 | Q9UKV8 (AGO2) | decreased_association | eFIP | 30567739 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R85 | W85 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y110 | S110 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| S195 | L195 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] |
