iPTMnet Report for Q9H0W8 (SMG9)
Protein Information
UniProt AC / UniProt ID | Q9H0W8 / SMG9_HUMAN |
Protein Name | Nonsense-mediated mRNA decay factor SMG9 |
Gene Name | Name: SMG9 Synonyms:C19orf61; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H0W8 |
PRO Name | nonsense-mediated mRNA decay factor SMG9 (human) |
Definition | A nonsense-mediated mRNA decay factor SMG9 that is encoded in the genome of human. |
Short Label | hSMG9 |
Category | organism-gene |
Q9H0W8 (SMG9) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 21406692, 20068231 | ||
S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S4 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983 | ||
S7 | Phosphorylation | score2 | IEDB phospho.ELM PhosphoSitePlus UniProt | 18691976, 21406692, 23186163, ... | ||
Y12 | Phosphorylation | score1 | PhosphoSitePlus | |||
K21 | Methylation | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S32 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
Y41 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21640080 | ||
S53 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
T114 | O-Glycosylation | score1 | GlyGen | 32938750, 35254053 | ||
T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
S117 | Phosphorylation | score1 | PhosphoSitePlus | |||
T118 | Phosphorylation | score1 | PhosphoSitePlus | |||
T122 | Phosphorylation | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y147 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15592455 | ||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
R248 | Methylation | score1 | PhosphoSitePlus | |||
C315 | Methylation | score1 | IEDB | 31844290 | ||
K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
C380 | Methylation | score1 | IEDB | 31844290 | ||
S451 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 18220336 | ||
K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
K508 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 20058876, ... | ||
S4 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S7 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 17081983, ... | ||
S32 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 19664994, ... | ||
S53 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648 | ||
Y147 | Phosphorylation | score0 | HPRD | 15592455 | ||
S451 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | C4 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
Y12 | C12 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S32 | C32 | Biomuta | [ cosmic ] | |
R248 | Q248 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] | |
C315 | W315 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
C315 | Y315 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |