iPTMnet Report for Q9H0W5 (CCDC8)
Protein Information
UniProt AC / UniProt ID | Q9H0W5 / CCDC8_HUMAN |
Protein Name | Coiled-coil domain-containing protein 8 |
Gene Name | Name: CCDC8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H0W5 |
PRO Name | coiled-coil domain-containing protein 8 (human) |
Definition | A coiled-coil domain-containing protein 8 that is encoded in the genome of human. |
Short Label | hCCDC8 |
Category | organism-gene |
Q9H0W5 (CCDC8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
S142 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S146 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 19664994, ... | ||
S273 | Phosphorylation | score1 | PhosphoSitePlus | |||
S302 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17525332 | ||
R320 | Methylation | score1 | PhosphoSitePlus | |||
R344 | Methylation | score1 | PhosphoSitePlus | |||
R445 | Methylation | score1 | PhosphoSitePlus | |||
T477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
K491 | Methylation | score1 | PhosphoSitePlus | |||
T499 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S103 | R103 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S146 | N146 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R320 | S320 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S487 | L487 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] | |
S487 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |