iPTMnet Report for Q9H0E2 (TOLLIP)
Protein Information
| UniProt AC / UniProt ID | Q9H0E2 / TOLIP_HUMAN |
| Protein Name | Toll-interacting protein |
| Gene Name | Name: TOLLIP |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H0E2 |
| PRO Name | Toll-interacting protein (human) |
| Definition | A Toll-interacting protein that is encoded in the genome of human. |
| Short Label | hTOLLIP |
| Category | organism-gene |
DAG ViewQ9H0E2 (TOLLIP) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S171 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K235 | Acetylation | score1 | PhosphoSitePlus | |||
| K235 | Ubiquitination | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | O75674 (TOM1L1) | S321 | Q9H0E2 (TOLLIP) | unknown | eFIP | 26899482 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S6 | N6 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
