Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0B8 / CRLD2_HUMAN
Protein Name Cysteine-rich secretory protein LCCL domain-containing 2 precursor
Gene Name Name: CRISPLD2
Synonyms:CRISP11,LCRISP2;ORFNames:UNQ2914/PRO1156/PRO9783;
Organism Homo sapiens (Human)

PRO ID PR:Q9H0B8
DAG View
PRO Name cysteine-rich secretory protein LCCL domain-containing 2 (human)
Definition A cysteine-rich secretory protein LCCL domain-containing 2 that is encoded in the genome of human.
Short Label hCRISPLD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0B8 (CRISPLD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N41 N-Glycosylation GlyGen 23090970, 24190977
T241 O-Glycosylation GlyGen 30459171
T254 O-Glycosylation GlyGen 30459171
Y283 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
Y468 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y283 Phosphorylation HPRD 17287340
T285 Phosphorylation HPRD 17287340
T292 Phosphorylation HPRD 17287340
S369 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T254 M254 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T322 S322 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
Y373 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y468 C468 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]