iPTMnet Report for Q9GZY6 (LAT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZY6 / NTAL_HUMAN
Protein Name Linker for activation of T-cells family member 2
Gene Name Name: LAT2
Synonyms:LAB,NTAL,WBS15,WBSCR15,WBSCR5;ORFNames:HSPC046;
Organism Homo sapiens (Human)

PRO ID PR:Q9GZY6
DAG View
PRO Name linker for activation of T-cells family member 2 (human)
Definition A linker for activation of T-cells family member 2 that is encoded in the genome of human.
Short Label hLAT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZY6 (LAT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y40 Phosphorylation PRO   PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus   UniProt 19369195
S51 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
T57 Phosphorylation IEDB   PhosphoSitePlus 28228285
Y58 Phosphorylation PRO   PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
Y84 Phosphorylation PRO   PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation P07948 (LYN) PRO   PhosphoSitePlus 17993265
K100 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation P10721 (KIT) , P07948 (LYN) PRO   PhosphoSitePlus 17993265
Y118 Phosphorylation P10721 (KIT) , P07948 (LYN) PRO   PhosphoSitePlus 17993265
Y119 Phosphorylation P07948 (LYN) PRO   PhosphoSitePlus 17993265
K126 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
Y136 Phosphorylation P07948 (LYN) , P43405 (SYK) phospho.ELM   PRO   PhosphoSitePlus   UniProt 17993265, 12486104, 14722116
C142 Methylation IEDB 31844290
S167 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation P43405 (SYK) phospho.ELM   PRO   PhosphoSitePlus   UniProt 17993265, 12486104, 14722116
S196 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation P43405 (SYK) phospho.ELM   PRO   PhosphoSitePlus   UniProt 17993265, 12486104, 14722116
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 20058876
Y136 Phosphorylation HPRD 16497976
Y193 Phosphorylation HPRD 16497976


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048169 (hLAT2/Phos:1) pY40,pY58,pY84,pY95,pY110,pY118,pY119,pY136,pY193,pY233 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S106 P106 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y118 H118 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S198 F198 Biomuta DOID:1324 / lung cancer [ cosmic ]
S205 P205 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]