iPTMnet Report for Q9GZM8 (NDEL1)
Protein Information
UniProt AC / UniProt ID | Q9GZM8 / NDEL1_HUMAN |
Protein Name | Nuclear distribution protein nudE-like 1 |
Gene Name | Name: NDEL1 Synonyms:EOPA,MITAP1,NUDEL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9GZM8 |
PRO Name | nuclear distribution protein nudE-like 1 (human) |
Definition | A nuclear distribution protein nudE-like 1 that is encoded in the genome of human. |
Short Label | hNDEL1 |
Category | organism-gene |
Q9GZM8 (NDEL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
T132 | Phosphorylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
S155 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 36254578 | ||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S198 | Phosphorylation | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
T219 | Phosphorylation | P06493 (CDK1) , P28482 (MAPK1) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18347064, 18669648, 20068231, ... | |
S231 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T241 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S242 | Phosphorylation | P06493 (CDK1) | score4 | neXtProt PhosphoSitePlus UniProt | 12556484, 20068231 | |
T245 | Phosphorylation | P28482 (MAPK1) , P06493 (CDK1) | score4 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 12556484, 18669648, 20068231 | |
S251 | Phosphorylation | O14965 (AURKA) | score4 | neXtProt RLIMS-P+ RLIMS-P | 17060449, 19668197, 20141511 | |
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
S282 | Phosphorylation | score1 | PhosphoSitePlus | |||
S285 | Phosphorylation | score0 | RLIMS-P | 36350697 | ||
T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
S306 | Phosphorylation | score1 | PhosphoSitePlus | |||
S332 | Phosphorylation | score0 | RLIMS-P | 31815665 | ||
S335 | Phosphorylation | score0 | RLIMS-P | 31815665 | ||
S336 | Phosphorylation | score0 | RLIMS-P | 31815665 | ||
S344 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S194 | Phosphorylation | score0 | HPRD | 19413330 | ||
S197 | Phosphorylation | score0 | HPRD | 19413330 | ||
S198 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 19413330, 12796778 | |
S208 | Phosphorylation | score0 | HPRD | 20068231 | ||
S215 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T219 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 12796778, 18669648, 20068231 | |
S231 | Phosphorylation | Q00535 (CDK5) | score1 | HPRD | 12796778 | |
T241 | Phosphorylation | score0 | HPRD | 18669648 | ||
S242 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 12796778, 20068231 | |
T245 | Phosphorylation | Q00535 (CDK5) | score2 | HPRD | 12796778, 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S194 | Phosphorylation | score0 | HPRD | 19413330 | ||
S197 | Phosphorylation | score0 | HPRD | 19413330 | ||
S198 | Phosphorylation | score0 | HPRD | 19413330 | ||
S208 | Phosphorylation | score0 | HPRD | 20068231 | ||
S215 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T219 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T241 | Phosphorylation | score0 | HPRD | 18669648 | ||
S242 | Phosphorylation | score0 | HPRD | 20068231 | ||
T245 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S135 | L135 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S162 | F162 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S194 | L194 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S197 | N197 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S208 | C208 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
T219 | I219 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K269 | N269 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S285 | Y285 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S285 | F285 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
S306 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S344 | T344 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic, cosmic ] DOID:1324 / lung cancer [ cosmic, cosmic, icgc, cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ] |