iPTMnet Report for Q9C0E2 (XPO4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0E2 / XPO4_HUMAN
Protein Name Exportin-4
Gene Name Name: XPO4
Synonyms:KIAA1721;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0E2
DAG View
PRO Name exportin-4 (human)
Definition An exportin-4 that is encoded in the genome of human.
Short Label hXPO4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0E2 (XPO4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y100 Phosphorylation PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
Y403 Phosphorylation PhosphoSitePlus
S464 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648
S521 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18767875, 19691289, 19651622, 18669648, 19690332, 20068231
S524 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231
S525 Phosphorylation HPRD   PhosphoSitePlus 19651622
T526 Phosphorylation HPRD   PhosphoSitePlus 18767875
S587 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
Y598 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S524 L524 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S524 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S603 Y603 Biomuta DOID:1319 / brain cancer [ cosmic ]