iPTMnet Report for Q9C0D5 (TANC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0D5 / TANC1_HUMAN
Protein Name Protein TANC1
Gene Name Name: TANC1
Synonyms:KIAA1728;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0D5
DAG View
PRO Name protein TANC1 (human)
Definition A protein TANC1 that is encoded in the genome of human.
Short Label hTANC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0D5 (TANC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S22 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus   UniProt 23186163
S66 Phosphorylation PhosphoSitePlus   UniProt 18669648
S67 Phosphorylation PhosphoSitePlus   UniProt 23186163
S79 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
T202 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus   UniProt 18669648
T211 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus   UniProt 23186163
T284 Phosphorylation PhosphoSitePlus
S291 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S300 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S313 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus   UniProt 23186163
K477 Ubiquitination PhosphoSitePlus
T478 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
K566 Methylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
T687 Phosphorylation PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
T809 Phosphorylation PhosphoSitePlus
C834 Methylation IEDB 31844290
K873 Ubiquitination PhosphoSitePlus
S1055 Phosphorylation PhosphoSitePlus
T1147 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation PhosphoSitePlus
K1176 Ubiquitination PhosphoSitePlus
K1209 Ubiquitination PhosphoSitePlus
K1361 Ubiquitination PhosphoSitePlus
K1380 Acetylation PhosphoSitePlus
C1400 Methylation IEDB 31844290
K1407 Ubiquitination PhosphoSitePlus
S1477 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1485 O-Glycosylation GlyGen 30379171
S1485 Phosphorylation PhosphoSitePlus
S1486 O-Glycosylation GlyGen 30379171
Y1487 Phosphorylation PhosphoSitePlus
S1497 Phosphorylation PhosphoSitePlus
S1503 Phosphorylation PhosphoSitePlus
S1513 Phosphorylation PhosphoSitePlus
K1535 Ubiquitination PhosphoSitePlus
S1537 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1542 Phosphorylation PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus
S1564 Phosphorylation P24941 (CDK2) , P28482 (MAPK1) neXtProt   PhosphoSitePlus 18847512, 22028470
T1590 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1659 Phosphorylation PhosphoSitePlus
S1662 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1665 Phosphorylation PhosphoSitePlus
S1668 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1671 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1676 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
S1678 Phosphorylation PhosphoSitePlus
S1685 Phosphorylation PhosphoSitePlus
S1687 Phosphorylation PhosphoSitePlus
K1704 Ubiquitination PhosphoSitePlus
S1814 O-Glycosylation GlyGen 30379171, 30059200, 35254053, ...34019948, 31492838, 35289036, 30620550, 29237092
Y1827 Phosphorylation PhosphoSitePlus
S1855 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation HPRD 20068231
S63 Phosphorylation HPRD 18669648, 20068231
S66 Phosphorylation HPRD 18669648, 20068231
S67 Phosphorylation HPRD 20068231
S207 Phosphorylation HPRD 18669648
S213 Phosphorylation HPRD 18669648
S214 Phosphorylation HPRD 18669648
T421 Phosphorylation HPRD 20068231
S444 Phosphorylation HPRD 20068231
S447 Phosphorylation HPRD 20068231
S448 Phosphorylation HPRD 20068231
T628 Phosphorylation HPRD 20068231
S1369 Phosphorylation HPRD 17081983
S1665 Phosphorylation HPRD 20068231
S1668 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S66 F66 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S79 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S85 Y85 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S217 T217 Biomuta DOID:1324 / lung cancer [ icgc ]
S217 Y217 Biomuta DOID:1324 / lung cancer [ icgc ]
T284 M284 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S291 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S300 C300 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T338 R338 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T421 M421 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S447 L447 Biomuta DOID:1324 / lung cancer [ cosmic ]
S447 A447 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S447 T447 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S465 L465 Biomuta DOID:4159 / skin cancer [ cosmic ]
T628 I628 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K873 N873 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1166 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K1407 T1407 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1485 C1485 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1486 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1513 F1513 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
S1537 G1537 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1564 T1564 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1662 G1662 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1676 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1678 L1678 Biomuta DOID:1612 / breast cancer [ icgc ]
S1814 F1814 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]