Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9C0D2 / CE295_HUMAN
Protein Name Centrosomal protein of 295 kDa
Gene Name Name: CEP295
Synonyms:KIAA1731;
Organism Homo sapiens (Human)

PRO ID PR:Q9C0D2
DAG View
PRO Name centrosomal protein of 295 kDa (human)
Definition A centrosomal protein of 295 kDa that is encoded in the genome of human.
Short Label hCEP295
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9C0D2 (CEP295) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
K23 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K259 Acetylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
K423 Acetylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
T553 Phosphorylation PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
S564 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
K652 Ubiquitination PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus   UniProt 23186163
K657 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K877 Ubiquitination PhosphoSitePlus
K904 Ubiquitination PhosphoSitePlus
S914 Phosphorylation PhosphoSitePlus
K935 Ubiquitination PhosphoSitePlus
S938 Phosphorylation PhosphoSitePlus   UniProt 23186163
K951 Ubiquitination PhosphoSitePlus
K961 Ubiquitination PhosphoSitePlus
Y975 Phosphorylation PhosphoSitePlus
K978 Ubiquitination PhosphoSitePlus
K1013 Ubiquitination PhosphoSitePlus
K1027 Ubiquitination PhosphoSitePlus
K1066 Ubiquitination PhosphoSitePlus
K1093 Ubiquitination PhosphoSitePlus
S1098 Phosphorylation PhosphoSitePlus
S1099 O-Glycosylation GlyGen 30379171, 29351928, 35254053
S1102 Phosphorylation PhosphoSitePlus
K1117 Ubiquitination PhosphoSitePlus
K1131 Ubiquitination PhosphoSitePlus
S1137 Phosphorylation IEDB 32387766
K1148 Ubiquitination PhosphoSitePlus
K1180 Ubiquitination PhosphoSitePlus
K1195 Ubiquitination PhosphoSitePlus
K1235 Ubiquitination PhosphoSitePlus
K1268 Ubiquitination PhosphoSitePlus
S1341 Phosphorylation PhosphoSitePlus
K1352 Ubiquitination PhosphoSitePlus
S1388 Phosphorylation PhosphoSitePlus
K1484 Ubiquitination PhosphoSitePlus
K1487 Ubiquitination PhosphoSitePlus
K1491 Ubiquitination PhosphoSitePlus
K1516 Ubiquitination PhosphoSitePlus
K1539 Ubiquitination PhosphoSitePlus
K1565 Ubiquitination PhosphoSitePlus
K1570 Ubiquitination PhosphoSitePlus
S1578 Phosphorylation PhosphoSitePlus
S1593 O-Glycosylation GlyGen 30379171, 29351928, 35254053
K1594 Ubiquitination PhosphoSitePlus
S1616 O-Glycosylation GlyGen 30379171, 29351928, 35254053
S1616 Phosphorylation PhosphoSitePlus
K1619 Ubiquitination PhosphoSitePlus
K1628 Ubiquitination PhosphoSitePlus
S1637 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1649 Ubiquitination PhosphoSitePlus
K1664 Ubiquitination PhosphoSitePlus
K1666 Ubiquitination PhosphoSitePlus
K1712 Ubiquitination PhosphoSitePlus
K1726 Ubiquitination PhosphoSitePlus
K1730 Ubiquitination PhosphoSitePlus
K1745 Ubiquitination PhosphoSitePlus
K1751 Ubiquitination PhosphoSitePlus
K1755 Ubiquitination PhosphoSitePlus
K1761 Ubiquitination PhosphoSitePlus
K1769 Ubiquitination PhosphoSitePlus
K1772 Ubiquitination PhosphoSitePlus
S1829 O-Glycosylation GlyGen 30379171, 29351928, 35254053
K1867 Ubiquitination PhosphoSitePlus
Y1871 Phosphorylation PhosphoSitePlus
Y1940 Phosphorylation PhosphoSitePlus
K2050 Ubiquitination PhosphoSitePlus
K2061 Ubiquitination PhosphoSitePlus
K2080 Ubiquitination PhosphoSitePlus
S2098 Phosphorylation PhosphoSitePlus
S2108 Phosphorylation PhosphoSitePlus
S2110 Phosphorylation PhosphoSitePlus
T2118 Phosphorylation PhosphoSitePlus
S2121 Phosphorylation PhosphoSitePlus
T2128 O-Glycosylation GlyGen 30379171, 29351928, 35254053
T2128 Phosphorylation PhosphoSitePlus
K2206 Ubiquitination PhosphoSitePlus
K2222 Ubiquitination PhosphoSitePlus
K2276 Ubiquitination PhosphoSitePlus
S2278 Phosphorylation PhosphoSitePlus
K2286 Ubiquitination PhosphoSitePlus
K2303 Ubiquitination PhosphoSitePlus
K2346 Ubiquitination PhosphoSitePlus
K2358 Ubiquitination PhosphoSitePlus
S2374 O-Glycosylation GlyGen 25813380
S2375 O-Glycosylation GlyGen 25813380
T2468 Phosphorylation PhosphoSitePlus
T2473 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2504 Ubiquitination PhosphoSitePlus
K2514 Ubiquitination PhosphoSitePlus
K2517 Ubiquitination PhosphoSitePlus
S2527 Phosphorylation PhosphoSitePlus
K2565 Ubiquitination PhosphoSitePlus
T2572 Phosphorylation PhosphoSitePlus
Y2577 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K47 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 E78 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K84 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K265 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K292 T292 Biomuta DOID:4362 / cervical cancer [ icgc ]
T415 R415 Biomuta DOID:4159 / skin cancer [ cosmic ]
K601 E601 Biomuta DOID:3571 / liver cancer [ cosmic ]
K858 N858 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K961 N961 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1098 C1098 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1388 F1388 Biomuta [ cosmic ]
K1594 N1594 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1619 R1619 Biomuta DOID:1319 / brain cancer [ cosmic ]
K1628 N1628 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1664 R1664 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1829 Y1829 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K2050 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2110 Y2110 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2110 F2110 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2118 A2118 Biomuta DOID:1324 / lung cancer [ cosmic ]