iPTMnet Report for Q9C004 (SPRY4)
Protein Information
UniProt AC / UniProt ID | Q9C004 / SPY4_HUMAN |
Protein Name | Protein sprouty homolog 4 |
Gene Name | Name: SPRY4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9C004 |
PRO Name | protein sprouty homolog 4 (human) |
Definition | A protein sprouty homolog 4 that is encoded in the genome of human. |
Short Label | hSPRY4 |
Category | organism-gene |
Q9C004 (SPRY4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22223895 | ||
T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y52 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 15584898 | ||
T77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
S125 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648 | ||
K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T77 | M77 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] |