iPTMnet Report for Q9BZD4 (NUF2)
Protein Information
UniProt AC / UniProt ID | Q9BZD4 / NUF2_HUMAN |
Protein Name | Kinetochore protein Nuf2 |
Gene Name | Name: NUF2 Synonyms:CDCA1,NUF2R; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BZD4 |
PRO Name | kinetochore protein Nuf2 (human) |
Definition | A kinetochore protein Nuf2 that is encoded in the genome of human. |
Short Label | hNUF2 |
Category | organism-gene |
Q9BZD4 (NUF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y37 | Phosphorylation | score1 | PhosphoSitePlus | |||
C99 | Methylation | score1 | IEDB | 31844290 | ||
C111 | Methylation | score1 | IEDB | 31844290 | ||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
S171 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
T242 | Phosphorylation | score1 | PhosphoSitePlus | |||
K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
S247 | Phosphorylation | score4 | HPRD IEDB phospho.ELM PhosphoSitePlus UniProt | 32897882, 23186163, 17081983, ... | ||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
T261 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
S329 | Phosphorylation | score1 | PhosphoSitePlus | |||
K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
K342 | Ubiquitination | score1 | PhosphoSitePlus | |||
K348 | Acetylation | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
C377 | Methylation | score1 | IEDB | 31844290 | ||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
K383 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y388 | Phosphorylation | score1 | PhosphoSitePlus | |||
K400 | Ubiquitination | score1 | PhosphoSitePlus | |||
K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
K427 | Ubiquitination | score1 | PhosphoSitePlus | |||
K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
K439 | Ubiquitination | score1 | PhosphoSitePlus | |||
K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
T464 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:O14777 (hNDC80) | Interaction | PR:Q9BZD4 (hNUF2) | PRO | ||
PR:Q02224 (hCENPE) | Interaction | PR:Q9BZD4 (hNUF2) | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K113 | Q113 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S171 | Y171 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
S171 | F171 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
S210 | F210 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S247 | Y247 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
T261 | M261 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
K309 | T309 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K335 | N335 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
C377 | Y377 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K409 | Q409 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
K409 | N409 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] |