iPTMnet Report Q9BYV7 BCO2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9BYV7 / BCDO2_HUMAN
Protein Name	Carotenoid-cleaving dioxygenase, mitochondrial
Gene Name	Name: BCO2 Synonyms:BCDO2;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9BYV7 DAG View
PRO Name	carotenoid-cleaving dioxygenase, mitochondrial (human)
Definition	A carotenoid-cleaving dioxygenase, mitochondrial that is encoded in the genome of human.
Short Label	hBCO2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9BYV7 (BCO2) as Substrate

Q9BYV7

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y34	Phosphorylation		score1	PhosphoSitePlus
	K124	Acetylation		score1	PhosphoSitePlus
	Y131	Phosphorylation		score1	PhosphoSitePlus
	K132	Acetylation		score1	PhosphoSitePlus
	S287	Phosphorylation		score1	PhosphoSitePlus
	Y294	Phosphorylation		score1	PhosphoSitePlus
	K405	Ubiquitination		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S287	R287	Biomuta		DOID:9256 / colorectal cancer [ icgc ]
S287	I287	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]