iPTMnet Report for Q9BYK8 (HELZ2)
Protein Information
UniProt AC / UniProt ID | Q9BYK8 / HELZ2_HUMAN |
Protein Name | Helicase with zinc finger domain 2 |
Gene Name | Name: HELZ2 Synonyms:KIAA1769,PRIC285; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BYK8 |
PRO Name | helicase with zinc finger domain 2 (human) |
Definition | A helicase with zinc finger domain 2 that is encoded in the genome of human. |
Short Label | hHELZ2 |
Category | organism-gene |
Q9BYK8 (HELZ2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
C59 | Methylation | score1 | IEDB | 31844290 | ||
C166 | Methylation | score1 | IEDB | 31844290 | ||
S334 | Phosphorylation | score1 | PhosphoSitePlus | |||
S338 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
T340 | Phosphorylation | score1 | PhosphoSitePlus | |||
T573 | Phosphorylation | score1 | PhosphoSitePlus | |||
S788 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y815 | Phosphorylation | score1 | PhosphoSitePlus | |||
T900 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1006 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
K1196 | Methylation | score1 | PhosphoSitePlus | |||
T1210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1304 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1315 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1325 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1503 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1507 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1564 | Methylation | score1 | PhosphoSitePlus | |||
Y1615 | Phosphorylation | score1 | PhosphoSitePlus | |||
C1707 | Methylation | score1 | IEDB | 31844290 | ||
S1751 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1955 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2021 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2152 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y2294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2295 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2296 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2390 | Ubiquitination | score1 | PhosphoSitePlus | |||
K2491 | Ubiquitination | score1 | PhosphoSitePlus | |||
K2505 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S338 | L338 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y735 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S788 | N788 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
K1196 | N1196 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
Y1304 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
T1315 | A1315 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
Y1615 | H1615 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S2021 | N2021 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S2296 | L2296 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K2390 | R2390 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] | |
K2491 | M2491 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] |