Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYJ4 / TRI34_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM34
Gene Name Name: TRIM34
Synonyms:IFP1,RNF21;
Organism Homo sapiens (Human)

PRO ID PR:Q9BYJ4
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM34 (human)
Definition An E3 ubiquitin-protein ligase TRIM34 that is encoded in the genome of human.
Short Label hTRIM34
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYJ4 (TRIM34) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K44 Ubiquitination PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
K93 Acetylation PhosphoSitePlus
K93 Methylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
C140 Methylation IEDB 31844290
K143 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
C239 Methylation IEDB 31844290
K273 Acetylation PhosphoSitePlus
K275 Acetylation PhosphoSitePlus
S317 Phosphorylation IEDB 35494241
K357 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K173 N173 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T185 A185 Biomuta DOID:1324 / lung cancer [ cosmic ]
K215 E215 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S317 L317 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K357 M357 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K357 N357 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]