iPTMnet Report for Q9BYG8 (GSDMC)
Protein Information
UniProt AC / UniProt ID | Q9BYG8 / GSDMC_HUMAN |
Protein Name | Gasdermin-C |
Gene Name | Name: GSDMC Synonyms:MLZE; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BYG8 |
PRO Name | gasdermin-C (human) |
Definition | A gasdermin-C that is encoded in the genome of human. |
Short Label | hGSDMC |
Category | organism-gene |
Q9BYG8 (GSDMC) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y26 | Phosphorylation | score1 | PhosphoSitePlus | |||
S84 | Phosphorylation | score1 | IEDB | 35494241 | ||
Y343 | Phosphorylation | score1 | PhosphoSitePlus | |||
S344 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | C3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S3 | F3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S84 | G84 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S344 | N344 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S344 | I344 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |