iPTMnet Report for Q9BY32 (ITPA)
Protein Information
UniProt AC / UniProt ID | Q9BY32 / ITPA_HUMAN |
Protein Name | Inosine triphosphate pyrophosphatase |
Gene Name | Name: ITPA Synonyms:C20orf37;ORFNames:My049,OK/SW-cl.9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BY32 |
PRO Name | inosine triphosphate pyrophosphatase (human) |
Definition | An inosine triphosphate pyrophosphatase that is encoded in the genome of human. |
Short Label | hITPA |
Category | organism-gene |
Q9BY32 (ITPA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
K19 | Acetylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y113 | Phosphorylation | score1 | PhosphoSitePlus | |||
C146 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
C154 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S4 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K9 | R9 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K19 | N19 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K39 | E39 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K39 | N39 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K56 | N56 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S111 | L111 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S111 | P111 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |