iPTMnet Report for Q9BXB4 (OSBPL11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXB4 / OSB11_HUMAN
Protein Name Oxysterol-binding protein-related protein 11
Gene Name Name: OSBPL11
Synonyms:ORP11,OSBP12;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXB4
DAG View
PRO Name oxysterol-binding protein-related protein 11 (human)
Definition An oxysterol-binding protein-related protein 11 that is encoded in the genome of human.
Short Label hOSBPL11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXB4 (OSBPL11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S13 Phosphorylation HPRD   PhosphoSitePlus 20166139
S15 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 23186163, 24275569
T27 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...19413330, 19664995, 18669648, 19690332, 20068231
S32 Phosphorylation PhosphoSitePlus
C34 S-Nitrosylation dbSNO 26338901
S43 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus   UniProt 19690332
S170 Phosphorylation PhosphoSitePlus
S172 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...18669648, 24275569, 19690332
S174 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S177 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S178 Phosphorylation PhosphoSitePlus
S179 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19664995, 20068231
S181 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18491316, 23186163, ...16964243, 18220336, 20058876, 19664994, 15302935, 19664995, 27869121, 19415658, 17322306, 18691976, 18669648, 19651622, 24275569, 18767875, 19690332, 20068231
S184 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
S189 Phosphorylation O14757 (CHEK1) HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18767875, 18077418, 19651622, 18669648, 21851590, 30784271, 20068231
S194 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
C240 Methylation IEDB 31844290
S286 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S333 Phosphorylation IEDB 32387766
K356 Ubiquitination PhosphoSitePlus
K395 Acetylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
C629 S-Nitrosylation dbSNO 26338901
K655 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
K738 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S13 L13 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T27 N27 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S43 C43 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S43 T43 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S172 G172 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S181 A181 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S184 L184 Biomuta DOID:1612 / breast cancer [ cosmic ]
S205 L205 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S207 N207 Biomuta DOID:1324 / lung cancer [ cosmic ]
S286 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S301 Y301 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S301 T301 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S333 Y333 Biomuta DOID:3571 / liver cancer [ cosmic ]
K655 E655 Biomuta DOID:9256 / colorectal cancer [ cosmic ]