iPTMnet Report for Q9BWH6 (RPAP1)
Protein Information
| UniProt AC / UniProt ID | Q9BWH6 / RPAP1_HUMAN |
| Protein Name | RNA polymerase II-associated protein 1 |
| Gene Name | Name: RPAP1 Synonyms:KIAA1403; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BWH6 |
| PRO Name | RNA polymerase II-associated protein 1 (human) |
| Definition | An RNA polymerase II-associated protein 1 that is encoded in the genome of human. |
| Short Label | hRPAP1 |
| Category | organism-gene |
DAG ViewQ9BWH6 (RPAP1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R38 | Methylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163 | ||
| S80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T321 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
| K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K518 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S601 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S603 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
| K623 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K780 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C1063 | Methylation | score1 | IEDB | 31844290 | ||
| S1064 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1086 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1093 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1116 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1121 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S1241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1337 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1367 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1377 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1382 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1384 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S72 | Phosphorylation | score0 | HPRD | 18691976, 20068231 | ||
| S80 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S266 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T268 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T321 | Phosphorylation | score0 | HPRD | 18691976, 19664994, 20068231 | ||
| S603 | Phosphorylation | score0 | HPRD | 15302935 | ||
| S1114 | Phosphorylation | score0 | HPRD | 15345747 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T268 | M268 | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S286 | F286 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K623 | R623 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| C1063 | F1063 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S1064 | L1064 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T1093 | M1093 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
| Y1377 | C1377 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
