Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BV94 / EDEM2_HUMAN
Protein Name ER degradation-enhancing alpha-mannosidase-like protein 2 precursor
Gene Name Name: EDEM2
Synonyms:C20orf31,C20orf49;ORFNames:UNQ573/PRO1135;
Organism Homo sapiens (Human)

PRO ID PR:Q9BV94
DAG View
PRO Name ER degradation-enhancing alpha-mannosidase-like protein 2 (human)
Definition An ER degradation-enhancing alpha-mannosidase-like protein 2 that is encoded in the genome of human.
Short Label hEDEM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BV94 (EDEM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K135 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K402 N402 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]