iPTMnet Report for Q9BUA3 (SPINDOC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUA3 / SPNDC_HUMAN
Protein Name Spindlin interactor and repressor of chromatin-binding protein
Gene Name Name: SPINDOC
Synonyms:C11orf84;
Organism Homo sapiens (Human)

PRO ID PR:Q9BUA3
DAG View
PRO Name spindlin interactor and repressor of chromatin-binding protein (human)
Definition A spindlin interactor and repressor of chromatin-binding protein that is encoded in the genome of human.
Short Label hSPINDOC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUA3 (SPINDOC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Sumoylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S82 Phosphorylation HPRD   PhosphoSitePlus 20068231
T117 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus   UniProt 23186163
S123 Phosphorylation HPRD 17081983
S148 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18452278, 19651622, 18669648, 19690332, 20068231
S152 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18452278, 19651622, ...18669648, 20068231
S154 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
K220 Sumoylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S248 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 19651622, ...18669648, 19690332, 20068231
S251 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 19651622, ...18669648, 20068231
T253 Phosphorylation HPRD   PhosphoSitePlus 19413330, 18669648, 20068231, ...19651622
T255 Phosphorylation HPRD   PhosphoSitePlus 19413330
K290 Sumoylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
S308 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 19664994, 19664995, 18669648, 19415658, 20068231
S310 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
T320 Phosphorylation PhosphoSitePlus
K374 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 N55 Biomuta DOID:1319 / brain cancer [ cosmic ]
S82 C82 Biomuta DOID:3571 / liver cancer [ cosmic ]
S123 Y123 Biomuta DOID:363 / uterine cancer [ icgc ]
T207 R207 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S248 L248 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T253 M253 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ]
T255 S255 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S308 R308 Biomuta DOID:10534 / stomach cancer [ cosmic ]