iPTMnet Report for Q9BTX1 (NDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTX1 / NDC1_HUMAN
Protein Name Nucleoporin NDC1
Gene Name Name: NDC1
Synonyms:TMEM48;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTX1
DAG View
PRO Name nucleoporin NDC1 (human)
Definition A nucleoporin NDC1 that is encoded in the genome of human.
Short Label hNDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTX1 (NDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C9 Methylation IEDB 31844290
S342 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S406 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18669648, 20068231
T410 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T414 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
K416 Ubiquitination PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
S432 Phosphorylation phospho.ELM 18669648
S435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation phospho.ELM 18669648
K437 Ubiquitination PhosphoSitePlus
S439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T440 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S445 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T449 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S453 Phosphorylation phospho.ELM 18669648
S471 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 16565220
S474 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 16565220
S487 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
S619 O-Glycosylation GlyGen 28411811, 34019948, 29351928
K628 Ubiquitination PhosphoSitePlus
K664 Ubiquitination PhosphoSitePlus
K673 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S344 L344 Biomuta DOID:4159 / skin cancer [ cosmic ]
K402 N402 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K416 R416 Biomuta DOID:363 / uterine cancer [ cosmic ]
S417 C417 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S424 L424 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K437 Q437 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S439 F439 Biomuta DOID:1324 / lung cancer [ cosmic ]
T440 A440 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S445 N445 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K673 N673 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]