iPTMnet Report for Q9BTT6 (LRRC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTT6 / LRRC1_HUMAN
Protein Name Leucine-rich repeat-containing protein 1
Gene Name Name: LRRC1
Synonyms:LANO;
Organism Homo sapiens (Human)

PRO ID PR:Q9BTT6
DAG View
PRO Name leucine-rich repeat-containing protein 1 (human)
Definition A leucine-rich repeat-containing protein 1 that is encoded in the genome of human.
Short Label hLRRC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTT6 (LRRC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus   UniProt 23186163
K487 Ubiquitination PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 L23 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S23 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T243 N243 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K272 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]