iPTMnet Report for Q9BTD8 (RBM42)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BTD8 / RBM42_HUMAN
Protein Name RNA-binding protein 42
Gene Name Name: RBM42
Organism Homo sapiens (Human)

PRO ID PR:Q9BTD8
DAG View
PRO Name RNA-binding protein 42 (human)
Definition An RNA-binding protein 42 that is encoded in the genome of human.
Short Label hRBM42
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BTD8 (RBM42) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
R130 Methylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus   UniProt 20068231
R139 Methylation PhosphoSitePlus
R145 Methylation PhosphoSitePlus
R146 Methylation PhosphoSitePlus
R153 Methylation PhosphoSitePlus   UniProt 24129315
R158 Methylation IEDB   PhosphoSitePlus   UniProt 24129315, 27503676
R168 Methylation PhosphoSitePlus   UniProt 24129315
R181 Methylation PhosphoSitePlus   UniProt 24129315
R186 Methylation PhosphoSitePlus
R225 Methylation PhosphoSitePlus
R306 Methylation PhosphoSitePlus
S406 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
T418 Phosphorylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
Y446 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S135 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R130 W130 Biomuta DOID:4159 / skin cancer [ cosmic ]
R130 Q130 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R139 Q139 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R145 W145 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R146 W146 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R146 Q146 Biomuta [ cosmic ]
R158 H158 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R181 H181 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R181 C181 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R186 Q186 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S406 C406 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y446 F446 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]